USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: TCPB_HUMAN USC-OGP 2-DE database:  TCPB_HUMAN TCPB_HUMAN General information about the entry View entry in simple text format Entry name TCPB_HUMAN Primary accession number P78371 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;. Gene name Name=CCT2 Synonyms=99D8.1, CCTB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0342: pI=5.96; Mw=55343 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0666: pI=5.91; Mw=51822 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1148: pI=6.34; Mw=55360 SPOT OGP-1154: pI=6.30; Mw=54155 Cross-references UniProtKB/Swiss-Prot P78371; TCPB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TCPB_HUMAN Primary accession number P78371 Secondary accession number(s) A8K402 B5BTY7 B7Z243 B7Z7K4 B7ZAT2 Q14D36 Q6IAT3 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 168) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta; Gene name Name=CCT2 Synonyms=99D8.1, CCTB Encoded on Name=CCT2; Synonyms=99D8.1, CCTB Keywords Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF026293; AAC96012.1; -; mRNA EMBL AF026166; AAC98906.1; -; mRNA EMBL BT019966; AAV38769.1; -; mRNA EMBL AK290767; BAF83456.1; -; mRNA EMBL AK294307; BAH11729.1; -; mRNA EMBL AK302157; BAH13640.1; -; mRNA EMBL AK316397; BAH14768.1; -; mRNA EMBL AK316408; BAH14779.1; -; mRNA EMBL CR457071; CAG33352.1; -; mRNA EMBL AB451223; BAG70037.1; -; mRNA EMBL AB451346; BAG70160.1; -; mRNA EMBL AC018921; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471054; EAW97230.1; -; Genomic_DNA EMBL BC113514; AAI13515.1; -; mRNA EMBL BC113516; AAI13517.1; -; mRNA EMBL U91327; AAB67249.1; -; Genomic_DNA CCDS CCDS55843.1; -. [P78371-2]; . CCDS CCDS8991.1; -. [P78371-1]; . RefSeq NP_001185771.1; NM_001198842.1. [P78371-2]; . RefSeq NP_006422.1; NM_006431.2. [P78371-1]; . UniGene Hs.189772; -; . ProteinModelPortal P78371; -; . BioGrid 115827; 258; . DIP DIP-38123N; -; . IntAct P78371; 125; . MINT MINT-8213815; -; . STRING 9606.ENSP00000299300; -; . iPTMnet P78371; -; . PhosphoSitePlus P78371; -; . SwissPalm P78371; -; . BioMuta CCT2; -; . DMDM 6094436; -; . OGP P78371; -; . REPRODUCTION-2DPAGE IPI00297779; -; . SWISS-2DPAGE P78371; -; . UCD-2DPAGE P78371; -; . EPD P78371; -; . PaxDb P78371; -; . PeptideAtlas P78371; -; . PRIDE P78371; -; . TopDownProteomics P78371-1; -. [P78371-1]; . DNASU 10576; -; . Ensembl ENST00000299300; ENSP00000299300; ENSG00000166226. [P78371-1]; . Ensembl ENST00000543146; ENSP00000445471; ENSG00000166226. [P78371-2]; . GeneID 10576; -; . KEGG hsa:10576; -; . UCSC uc010stl.2; human. [P78371-1]; . CTD 10576; -; . DisGeNET 10576; -; . GeneCards CCT2; -; . HGNC HGNC:1615; CCT2; . HPA HPA003197; -; . HPA HPA003198; -; . MIM 605139; gene; . neXtProt NX_P78371; -; . OpenTargets ENSG00000166226; -; . PharmGKB PA26179; -; . eggNOG KOG0363; Eukaryota; . eggNOG COG0459; LUCA; . GeneTree ENSGT00550000074930; -; . HOGENOM HOG000226736; -; . HOVERGEN HBG001052; -; . InParanoid P78371; -; . KO K09494; -; . OMA YNYPEQI; -; . OrthoDB EOG091G07BP; -; . PhylomeDB P78371; -; . TreeFam TF105645; -; . Reactome R-HSA-389957; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-390450; Folding of actin by CCT/TriC; . Reactome R-HSA-390471; Association of TriC/CCT with target proteins during biosynthesis; . Reactome R-HSA-5620922; BBSome-mediated cargo-targeting to cilium; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; . SIGNOR P78371; -; . ChiTaRS CCT2; human; . GeneWiki CCT2_(gene); -; . GenomeRNAi 10576; -; . PRO PR:P78371; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000166226; -; . CleanEx HS_CCT2; -; . ExpressionAtlas P78371; baseline and differential; . Genevisible P78371; HS; . GO GO:0035578; C:azurophil granule lumen; TAS:Reactome; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005832; C:chaperonin-containing T-complex; IDA:UniProtKB; . GO GO:0005829; C:cytosol; NAS:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0044183; F:protein binding involved in protein folding; IPI:BHF-UCL; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:ParkinsonsUK-UCL; . GO GO:0051082; F:unfolded protein binding; NAS:UniProtKB; . GO GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl; . GO GO:0051086; P:chaperone mediated protein folding independent of cofactor; IMP:BHF-UCL; . GO GO:0051131; P:chaperone-mediated protein complex assembly; IMP:MGI; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:1904851; P:positive regulation of establishment of protein localization to telomere; IMP:BHF-UCL; . GO GO:1904871; P:positive regulation of protein localization to Cajal body; IMP:BHF-UCL; . GO GO:0051973; P:positive regulation of telomerase activity; IMP:BHF-UCL; . GO GO:1904874; P:positive regulation of telomerase RNA localization to Cajal body; IMP:BHF-UCL; . GO GO:0032212; P:positive regulation of telomere maintenance via telomerase; IMP:BHF-UCL; . GO GO:0006457; P:protein folding; NAS:UniProtKB; . GO GO:0050821; P:protein stabilization; IMP:BHF-UCL; . GO GO:0090666; P:scaRNA localization to Cajal body; IMP:BHF-UCL; . GO GO:1901998; P:toxin transport; IEA:Ensembl; . CDD cd03336; TCP1_beta; 1; . Gene3D 1.10.560.10; -; 2; . Gene3D 3.30.260.10; -; 2; . Gene3D 3.50.7.10; -; 1; . InterPro IPR012716; Chap_CCT_beta; . InterPro IPR017998; Chaperone_TCP-1; . InterPro IPR002194; Chaperonin_TCP-1_CS; . InterPro IPR002423; Cpn60/TCP-1; . InterPro IPR027409; GroEL-like_apical_dom; . InterPro IPR027413; GROEL-like_equatorial; . InterPro IPR027410; TCP-1-like_intermed; . PANTHER PTHR11353:SF119; PTHR11353:SF119; 1; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00304; TCOMPLEXTCP1; . SUPFAM SSF52029; SSF52029; 1; . TIGRFAMs TIGR02341; chap_CCT_beta; 1; . PROSITE PS00750; TCP1_1; 1; . PROSITE PS00751; TCP1_2; 1; . PROSITE PS00995; TCP1_3; 1; .

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